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Atropine antidote for full#

Summary of evaluation and recommendationsġ2.3 Other consequential or supportive therapyġ2.4 Controversial issues and areas of use where there is insufficient information to make recommendationsġ3.4 Pharmaceutical incompatibilities and drug interactionsĪtropine is the best-known member of a group of drugs known as muscarinic antagonists, which are competitive antagonists of acetylcholine at muscarinic receptors. Pharmaceutical formulation and synthesisĥ.2 Methods for identification of antidoteĥ.3 Methods for analysis of atropine in biological samplesĥ.4 Methods for analysis of the toxic agent in biological samplesġ1.1 Dose and duration of atropine sulphate therapyġ1.3 Assessment of optimal atropinizationġ1.5 Role of other anticholinergic agentsġ2.

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Atropine antidote for full#

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Atropine antagonizes effects of cholinergic drugs when administered togetherĪtropine is present in Atropa belladonna leaves.

Single dose in Relieve broncho-constriction in horses (equine asthma syndrome).

Antidote for organophosphate and carbamate poisoning.

Decrease Gastro intestinal motility (Antispasmodic).

Cattle: 0.02 mg/kg to 0.04 mg/kg q6hr IV, SC, IMįor organophosphate and carbamate poisoning treatment in dogs and cats, a dose of atropine can be given up to 0.5 mg/kg, and for organophosphate and carbamate poisoning in horses, pigs, and ruminants (cattle, sheep, and goats), a dose of atropine can be given up to 0.04 mg/kg.

Sheep and Goats: 0.02 mg/kg to 0.04 mg/kg q6hr IV, SC, IM.

Pigs: 0.02 mg/kg to 0.04 mg/kg q6hr IV, SC, IM.

Horses: 0.02 mg/kg to 0.04 mg/kg q6hr IV, SC, IM.

Cats: 0.02 mg/kg to 0.04 mg/kg q6hr IV, SC, IM.

Dogs: 0.02 mg/kg to 0.04 mg/kg q6hr IV, SC, IM.

Mechanism of ActionĪtropine blocks acetylcholine (ACh) at muscarinic receptors and produce Antivagal effects. GroupĪtropine is grouped in Anticholinergic (Parasympatholytic) and Muscarinic receptor antagonists agent.

Atropine is a natural Anticholinergic (Parasympatholytic) and Muscarinic receptor antagonists agent that is present in Atropa belladonna leaves and in some other plants of the Solanaceae family.